Surface Plasmon Resonance (SPR) is a super handy, no-label method for checking out how biomolecules interact in real-time. It picks up on shifts in the refractive index at a sensor chip's surface, letting you measure the binding between molecules precisely. SPR is often seen as the go-to method for analyzing interactions because it gives you detailed kinetic and affinity data without needing to tweak the molecules.
more: https://www.profacgen.com/surf....ace-plasmon-resonanc