Even though this might seem somewhat obvious, playing friends have the potential to help make content easier. You might have an easier time as long as your friends and you have builds that will handle themselves. When you play co-op, Path of Exile increases the quantity of Path of exile currency loot that creatures fall when murdered. Additionally, monsters get tougher to kill. If you've got a very weak construct this can present a problem, but running with players will normally make the game. If you'd like the maximum loot out of every map, celebration play is the best way to go.
You may be unable to discover things you need while playing Path of Exile, but it's possible to craft modifiers onto items you are wearing fixing any problems. Need life? Craft life on your equipment. Is it true that your weapon require a level damage roll to deal harm? Craft it! All of your things need is a modifier onto it rather than a full replacement. For the endgame also, with master mods allowing gamers to craft some things that are powerful, rivaling Ascendency passives this goes!
Do not underestimate how powerful your flasks are in Path of Exile. Life flasks provide a lot of regeneration fast, but usefulness flasks can offer lots of defensives for your own character. Granite flasks can provide you plenty of armor to mitigate bodily harm, while Jade flasks can provide evasion that is needed to dodge attacks. Flasks can blind enemies that are nearby, halving their opportunity to strike you. Contrary to POE currency buy ARPGs like Diablo, flasks in Path of Exile recharge based on murdering enemies, so you can have these strong buffs busy, if you kill.