While Tadalafil may be effective for many patients, alternatives such as phosphodiesterase-5 inhibitors (e.g., sildenafil) or selective serotonin reuptake inhibitors (e.g., sertraline) may be preferable for individuals with a history of priapism. Lifestyle modifications, including smoking cessation and alcohol moderation, can also complement pharmacological interventions in managing erectile dysfunction and premature ejaculation.
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